Neuroleptics in dementia
نویسندگان
چکیده
منابع مشابه
Efficacy and safety of neuroleptics in behavioral disorders associated with dementia.
BACKGROUND Neuroleptics are commonly used to treat behavioral disorders associated with dementia. However, their safety and efficacy have not been well established in these patients. METHOD A meta-analysis of randomized, controlled (either placebo or active drug), double-blind trials published since 1966 (N = 16; 499 treated, 112 active controls, and 123 placebo) was conducted. Data were coll...
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A study was conducted on 66 psychiatric inpatients who took major tranquilizers for periods of four to 16 years. The frequency of signs of Parkinsonism and the effects of orphenadrine on these were studied in a double-blind crossover method. Sixty-one per cent of the patients showed signs of Parkinsonism. Female patients and those with organic brain pathology more frequently exhibited Parkinson...
متن کاملUse of neuroleptics in a general hospital
BACKGROUND This study investigates the clinical use of neuroleptics within a general hospital in acutely ill medical or surgical patients and its relation with dementia three months after admission compared with control subjects. METHODS Cases were defined as every adult patient to whom a neuroleptic medication was prescribed during their hospitalization in our Hospital from February 1st, to ...
متن کاملA Randomised, Blinded, Placebo-Controlled Trial in Dementia Patients Continuing or Stopping Neuroleptics (The DART-AD Trial)
BACKGROUND There have been increasing concerns regarding the safety and efficacy of neuroleptics in people with dementia, but there are very few long-term trials to inform clinical practice. The aim of this study was to determine the impact of long-term treatment with neuroleptic agents upon global cognitive decline and neuropsychiatric symptoms in patients with Alzheimer disease. METHODS AND...
متن کاملThe neuroleptics: a historical survey.
The history of the neuroleptic drugs has been marked by various milestones: some have been successes, others have been associated with complications and side effects, especially when the drugs have been misused. At the Paris meeting in 1955, it was confirmed that neuroleptics were indicated in chronic psychoses. In 1963, a new form of long-acting neuroleptic was introduced which appeared useful...
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ژورنال
عنوان ژورنال: Psychiatric Bulletin
سال: 1999
ISSN: 0955-6036,1472-1473
DOI: 10.1192/pb.23.7.409